The genomics of colorectal cancer in populations with African and European ancestry

PA Myer, JK Lee, RW Madison, K Pradhan… - Cancer discovery, 2022 - AACR
… cancer in Blacks can be attributed to increased rates of obesity, … The genomic contribution to
disparities in colorectal cancer … EUR to denote individuals of African and European ancestry, …

[HTML][HTML] Genetics of hypertension in African Americans and others of African descent

M Zilbermint, F Hannah-Shmouni… - International journal of …, 2019 - mdpi.com
… in an African American person with hypertension is a low or high … It has been speculated that
several genes implicated in the … genetic contributions to hypertension in African Americans. …

[HTML][HTML] Evaluating the promise of inclusion of African ancestry populations in genomics

AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
… in genomic research, 10 we here use “individuals of African … substantial contributions to
increasing diversity in genomic … area of genomic research in which increased diversity is vital …

Investigating mitonuclear interactions in human admixed populations

AA Zaidi, KD Makova - Nature ecology & evolution, 2019 - nature.com
… admixed individuals by the 1000 Genomes Admixture Group … enrichment in European
ancestry at high-mt genes in … a high level of concordance between the female contribution

[HTML][HTML] Does the high prevalence of vitamin D deficiency in African Americans contribute to health disparities?

BN Ames, WB Grant, WC Willett - Nutrients, 2021 - mdpi.com
… include most people with dark skin living at high latitudes, … low at high latitudes, as in
the United States and Europe, and … by activating or inactivating their adjacent genes [16,17,18]; …

[PDF][PDF] Genetic consequences of the transatlantic slave trade in the Americas

SJ Micheletti, K Bryc, SGA Esselmann… - The American Journal of …, 2020 - cell.com
… platforms and Human Genome Diversity Panel individuals (HGDP)… A high proportion of
individuals from the Guianas (64%) and … European male and African female genetic contributions

[HTML][HTML] Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank

…, A Moscati, JE Rodriguez, CBIPM Genomics Team… - Genome Medicine, 2020 - Springer
… variants in non-European populations, and suggest that genomic screening in diverse patient
… The high proportion of AJ individuals in our cohort (14.0%) contributed to the high overall …

A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa

M Harlemon, O Ajayi, P Kachambwa, MS Kim… - Cancer research, 2020 - AACR
… In summary, individual and population-level differences in … much greater for African genomes
than European genomes (… , identify loci that contribute to population-level differences in …

[HTML][HTML] Genotyping, sequencing and analysis of 140,000 adults from Mexico City

A Ziyatdinov, J Torres, J Alegre-Díaz, J Backman… - Nature, 2023 - nature.com
… We describe high levels of relatedness … -genome sequencing, we developed an imputation
reference panel that outperforms existing panels at common variants in individuals with high

[PDF][PDF] The genomic impact of European colonization of the Americas

L Ongaro, MO Scliar, R Flores, A Raveane, D Marnetto… - Current Biology, 2019 - cell.com
… Here, we compiled a genome-wide dataset of $12,000 individuals from twelve … We revealed
a high degree of complexity underlying the genetic contribution of European and African